Coronary artery bypass graft in a patient with Von Willebrand disease type 1

Von Willebrand disease (VWD), is the most common hereditary bleeding disorder (HBD) and affects approximately 1–2% of population. Type 1 accounts for 70–80% all cases involves partially reduced levels functional VWF. It usually manifested by mild to moderate mucocutaneous bleeding. A 63-yearold patient with multivessel coronary artery diagnosed Willebrand’s type after a previous NSTEMI infarction (10 days earlier) was admitted cardiac surgery department planned CABG procedure. The coagulation factor values on admission ward were successively (VIII 15%; VWF: Ag 12%). Coronary angiography revealed MV CAD. consulted HEART Team. decision made qualify using OPCAB technique. detailed plan securing haemostasis established. Haemate P 500/1200 1000/2400, lyophilized concentrate humans VIII von Factors, secured. During surgery, LITA- LAD Ao- RCA bridges performed Medtronic Starfish® Heart Positioners. In post-operation period, no complications noted. Plasma VW factors measured daily antihemorrhagic prophylaxis given accordingly values. discharged eighth day in good condition, haematological recommendations. Currently, there are guidelines management patients undergoing surgery. Incorrectly conducted pharmacotherapy may result an elevated level additional exposure occurrence acute syndromes heart attacks.